Enzymes are powerful natural cleaning agents used to break down and reduce tough stains, clogs, and odors. If you’re struggling to clean grease buildup in your drains, a good enzyme drain cleaner can help. Enzyme-based cleaners use biological enzymes to target grease and oil buildup and liquefy it for easy and thorough cleaning. In this guide, we’ll discuss what to look for when choosing the best enzyme drain cleaner for grease, and review some of the best products on the market.

Best Enzyme Drain Cleaner For Grease

Rank Product Name Score
1
ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs
ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs
9. 7
2
Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White
Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White
9. 5
3
Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance.
Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance.
9. 1
4
Liquid Clog Remover By Green Gobbler - Drain, Toilet Clog Remover, DISSOLVE Hair & Grease From Clogged Toilets, Sinks And Drains - Drain Cleaner, Works Within Minutes - 1 Gallon
Liquid Clog Remover By Green Gobbler – Drain, Toilet Clog Remover, DISSOLVE Hair & Grease From Clogged Toilets, Sinks And Drains – Drain Cleaner, Works Within Minutes – 1 Gallon
8. 8
5
DrainScrub Powder Enzyme Drain Cleaner and Septic Treatment Environmentally Friendly Bacteria Unclog and Deodorize Pipes (2 lbs)
DrainScrub Powder Enzyme Drain Cleaner and Septic Treatment Environmentally Friendly Bacteria Unclog and Deodorize Pipes (2 lbs)
8. 6
6
Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps (1 Gallon)
Green Gobbler ENZYMES for Grease Trap & Sewer – Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps (1 Gallon)
8. 2
7
AmazonCommercial Drain and Grease Trap Cleaner and Maintainer, 1-Gallon, 1-Pack
AmazonCommercial Drain and Grease Trap Cleaner and Maintainer, 1-Gallon, 1-Pack
8. 0
8
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
7 .7
9
48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Septic Tank Safe Prevent Expensive Sewage Backups for Kitchen Bathroom Toilet Showers
48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Septic Tank Safe Prevent Expensive Sewage Backups for Kitchen Bathroom Toilet Showers
7. 4
10
Green Gobbler Liquid Hair & Grease Clog Remover | Drain Opener | Drain cleaner | Toilet Clog Remover - 2 Pack
Green Gobbler Liquid Hair & Grease Clog Remover | Drain Opener | Drain cleaner | Toilet Clog Remover – 2 Pack
7. 2

1. ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs

ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs

9.7/10 our score

I recently tried out ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs, and I am so glad I did! This is an amazing, eco-friendly product that really works. It helped unclog my drains and left them smelling fresh, too. It’s made with natural enzymes and doesn’t have any harsh chemicals. It’s also great for regular maintenance and will help prevent future clogs. I highly recommend this product for anyone looking for an eco-friendly way to keep their drains clean and clear. Highly recommended!

  • Contains natural enzymes which break down organic waste, grease, and soap scum
  • Safe for all types of pipes, septic tanks, and drains
  • No harsh chemicals or odors
  • Biodegradable and non-toxic
  • 2lb container

2. Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White

Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White

9.5/10 our score

I recently purchased the Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with a Pleasant Scent and the 1 Gallon Bottle in a Milky White color. I have to say, I am thoroughly impressed with this product! It quickly and efficiently cleared away any build up in my drain and left a pleasant scent behind. The milky white color also adds a nice touch to the bathroom decor. I would highly recommend this product to anyone looking for an effective and affordable drain cleaner.

  • Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent
  • 1 Gallon Bottle, Milky White
  • Breaks down grease, fats, oils, and food particles
  • Safe for use on all pipes, septic systems and sewer lines
  • Non-acid, non-caustic, non-phosphorus, non-flammable, non-toxic and biodegradable
  • Leaves behind a pleasant scent
  • Ideal for use in kitchens, bathrooms, laundry rooms and more

3. Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance.

Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance.

9.1/10 our score

I recently purchased Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance and have been really impressed with the results. It is a powerful cleaner that has been specifically designed to clean grease traps and reduce odors. The product comes in a liquid concentrate which you mix with water and then pour down the drain. The directions are easy to follow and the product worked quickly and effectively. The odor was drastically reduced after only a few treatments and the grease trap was completely clean after a few weeks. I highly recommend this product for anyone looking for a reliable and effective cleaner for their grease trap.
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  • Effective enzyme-based cleaner designed to break down grease, oils, fats, and other organic matter.
  • Formulated with industrial strength bacteria strains to quickly break down tough grease.
  • Safe and effective for commercial or residential use.
  • Eliminates odors from grease traps, floor drains and sink drains.
  • Reduces maintenance and cleaning costs for grease traps.
  • Helps to maintain clean and healthy grease traps.
  • Environmentally-friendly, biodegradable and non-toxic.
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4. Liquid Clog Remover By Green Gobbler – Drain, Toilet Clog Remover, DISSOLVE Hair & Grease From Clogged Toilets, Sinks And Drains – Drain Cleaner, Works Within Minutes – 1 Gallon

Liquid Clog Remover By Green Gobbler - Drain, Toilet Clog Remover, DISSOLVE Hair & Grease From Clogged Toilets, Sinks And Drains - Drain Cleaner, Works Within Minutes - 1 Gallon

8.8/10 our score

I recently purchased Green Gobbler’s Liquid Clog Remover and it has been a miracle worker! I had a really stubborn clog in my sink that I just couldn’t seem to get rid of no matter what I tried. With the Liquid Clog Remover, I was able to get it unclogged in minutes. It’s a great product and I’m glad I invested in it. It’s so much easier and quicker than dealing with traditional drain cleaners. Highly recommended!

  • Dissolve Hair and Grease: Green Gobbler’s Liquid Clog Remover quickly and easily dissolves hair, grease, soaps, and paper products that have built up in drains and toilets.
  • Works Within Minutes: This fast-acting product begins to work within minutes of application, breaking down obstructions in your drain or toilet for easy removal.
  • Safe for All Pipes: This non-corrosive, non-acidic formula is safe for all types of pipes, including PVC, galvanized steel, copper, brass, and aluminum.
  • Larger Size: This liquid clog remover comes in a 1 gallon size, giving you enough liquid to clear multiple clogged drains without having to purchase multiple containers.

5. DrainScrub Powder Enzyme Drain Cleaner and Septic Treatment Environmentally Friendly Bacteria Unclog and Deodorize Pipes (2 lbs)

DrainScrub Powder Enzyme Drain Cleaner and Septic Treatment Environmentally Friendly Bacteria Unclog and Deodorize Pipes (2 lbs)

8.6/10 our score

I recently gave DrainScrub Powder Enzyme Drain Cleaner and Septic Treatment Environmentally Friendly Bacteria Unclog and Deodorize Pipes (2 lbs) a try, and I am so glad I did! This product is amazing – it unclogged my drain in a matter of minutes with no scrubbing or harsh chemicals required. It is also very environmentally friendly, as it is made with natural enzymes and bacteria, so I know that I am not harming the environment. Plus, it deodorized my pipes, leaving my home smelling fresher than it ever has before. I would definitely recommend this product to anyone looking for an effective and environmentally-friendly way to unclog and deodorize their pipes!

list

  • Powder Enzyme Drain Cleaner and Septic Treatment
  • Environmentally Friendly Bacteria
  • Unclog and Deodorize Pipes
  • 2 lbs

6. Green Gobbler ENZYMES for Grease Trap & Sewer – Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps (1 Gallon)

Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps (1 Gallon)

8.2/10 our score

I recently bought the 6. Green Gobbler Enzymes for Grease Trap & Sewer and it has worked wonders! I have been having issues with odor and buildup in my sewer lines and septic tanks, and this product has been a lifesaver. It is designed to control foul odors and break down grease, paper, fat, and oil. I have noticed a significant decrease in odors, and the grease, paper, fat, and oil have been broken down quickly and effectively. I am very pleased with the results and would definitely recommend this product to anyone looking to clean and maintain their sewer lines and septic tanks.

  • 100% Natural Enzyme Formula
  • Eliminates Foul Odors
  • Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps
  • 1 Gallon (128 Fl Oz) Bottle
  • Safe for Septic Systems & Water Treatment Plants
  • Non-Toxic, Biodegradable & Eco-Friendly

7. AmazonCommercial Drain and Grease Trap Cleaner and Maintainer, 1-Gallon, 1-Pack

AmazonCommercial Drain and Grease Trap Cleaner and Maintainer, 1-Gallon, 1-Pack

8/10 our score

I recently purchased the AmazonCommercial Drain and Grease Trap Cleaner and Maintainer and I’m so glad I did. It has made cleaning my drains and grease traps much easier and faster. I love that it comes in a 1 gallon container so it lasts a long time and it’s very easy to use. I highly recommend this product to anyone who wants to keep their drains and grease traps clean and well-maintained. It’s definitely worth the investment!

  • Powerful chemical formula for cleaning and maintaining drain and grease traps.
  • Safe to use on all types of drains and grease traps.
  • Eliminates odors caused by grease and other organic material.
  • Removes grease, fats, oils, and other organic material build-up.
  • Easy and ready-to-use – no mixing, diluting or activation required.
  • Can be used on a regular basis to prevent build-up and clogging.
  • Comes in 1-gallon size and 1-pack.
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8. AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack

AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack

7.7/10 our score

I recently purchased the AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack, and so far I’m loving it. This enzyme cleaner is an amazing product that works well on any surface, and it’s very easy to use. It’s also safe to use around kids and pets, so I feel comfortable using it in my home. The cleaner has a pleasant smell and is biodegradable, so it’s also environmentally friendly. The 1-Gallon bottle also lasts a long time, so I don’t have to worry about constantly buying more. I’m really impressed with this cleaner and would highly recommend it to anyone looking for an all-purpose cleaner.

  • Kills 99.9% of bacteria, fungi, and viruses
  • Formulated for a wide range of surfaces, including carpets, floors, and walls
  • Fragrance-free and dye-free
  • Safe for use around children and pets
  • Non-toxic and biodegradable
  • No harsh chemicals or fumes
  • 1-gallon container with included 1-pack
  • Non-irritating to eyes, skin, and respiratory system

9. 48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Septic Tank Safe Prevent Expensive Sewage Backups for Kitchen Bathroom Toilet Showers

48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Septic Tank Safe Prevent Expensive Sewage Backups for Kitchen Bathroom Toilet Showers

7.4/10 our score

I recently purchased the 48PCS Drain Cleaner Sticks and I’m so glad I did! They have been a lifesaver in my bathroom and kitchen sinks to unclog drains and keep them smelling fresh. The organic enzymes are safe for my septic tank and are a great way to prevent expensive sewage backups. They are so easy to use, just pop one of the sticks in the drain and let it do its work! I’ve noticed a significant reduction in clogs and a fresher smell in my bathroom and kitchen. Highly recommend these drain cleaner sticks!

  • Offers quick and easy drain cleaning with no harsh chemicals
  • Comes with 48PCS drain cleaner sticks to tackle stubborn clogs
  • Safe for septic tanks and prevents expensive sewage backups
  • The organic enzymes break down hairs, grease, fats and other organic buildup
  • Eliminates sink odors and leaves the sink smelling fresh
  • Suitable for kitchen, bathroom, toilet, and shower drains

10. Green Gobbler Liquid Hair & Grease Clog Remover | Drain Opener | Drain cleaner | Toilet Clog Remover – 2 Pack

Green Gobbler Liquid Hair & Grease Clog Remover | Drain Opener | Drain cleaner | Toilet Clog Remover - 2 Pack

7.2/10 our score

I recently purchased the Green Gobbler Liquid Hair & Grease Clog Remover | Drain Opener | Drain Cleaner | Toilet Clog Remover – 2 Pack and was very impressed. I had been dealing with clogged drains in my home and was looking for an effective and affordable solution. After using this product, I was delighted to find that it worked quickly and efficiently to unclog my drains. The instructions on the packaging were easy to follow, and the solution did not have an unpleasant smell. I was very happy with the results, and would recommend the Green Gobbler Liquid Hair & Grease Clog Remover to anyone dealing with clogged drains. It is a great value and is a very effective way to clean and unclog your drains.

  • Instantly opens slow drains & liquifies hair and grease
  • Harmless to pipes and septic systems
  • Fast-acting, non-corrosive formula
  • Safe for all pipes, septic tanks and garbage disposals
  • Non-flammable, non-toxic, and odorless
  • 100% biodegradable and environmentally friendly
  • Great for kitchen sinks, bathtubs, showers, and toilet clogs
  • Comes in a convenient 2 pack
  • Easy to use and easy to store
  • Formulated with natural citrus extracts